SPR Target Onboarding

URL: https://cloud.ginkgo.bio/protocols/spr-target-onboarding Service terms: https://cloud.ginkgo.bio/terms/spr-target-onboarding Reviewed: 2026-09-30; prices and turnaround below are catalog estimates. Status: Beta Price: $1,399/target Turnaround: up to 4 weeks

Launch offer: Terms restrict the credit to successful qualification and the first binding run against the same target lot; it expires 12 months after qualification. Confirm availability and the accepted order's terms.

Overview

Qualifies a target on the Cloud Lab SPR (surface plasmon resonance) catalog for kinetic profiling against your binder candidates. Ginkgo procures the target and reference binder, selects capture chemistry, validates immobilization and surface activity on the Nicoya Alto, scouts regeneration conditions, and releases a qualified method to the catalog. Once onboarded, the target can be used in downstream kinetics/binding assay runs.

Onboarding does not screen the customer's binder library. Confirm the target's live qualification status and availability of the separate binding service; a queued or in-progress target is not qualified. The current launch scope uses commercial target/reference-binder standards and starts downstream screening with minibinders.

Input

(Use the provided .xlsx template; list each target on its own row for multi-target orders.)

• Target catalog number (vendor + SKU)
• Reference binder catalog number (vendor + SKU)
• Target metadata (MW, oligomeric state, sensitivities)
• Buffer preferences, if any
• Usable capture handle or amine-coupling requirement; reference-binder affinity if known
• Use approved vendors/SKUs or request vendor qualification; customer-supplied target/binder material is outside the launch scope

Output

• Validated capture method and surface conditions
• Recommended assay parameters for downstream kinetics runs
• Qualification report with pass/fail call and remediation if needed

Automated Workflow

Phase 1 - Intake & Procurement

1. Catalog number intake (Nebula Core)
2. Vendor procurement (Nebula Core)

Phase 2 - Surface Setup & Validation

1. Capture chemistry selection (project scientist)
2. Test immobilization (Nicoya Alto)
3. Surface activity check (Nicoya Alto)
4. Regeneration scouting (Nicoya Alto)

Phase 3 - Qualification & Release

1. Qualification record (LIMS)
2. Release to catalog (project scientist)

Ordering

• Number of Targets: configurable ($1,399/target)
• File Upload: .xlsx only (use the provided template)
• Additional Details: free-text field for special requirements

Use Cases

• Preparing a target for SPR kinetic profiling of binder candidates
• Establishing capture/regeneration conditions before binding campaigns
• Onboarding a target ahead of antibody/minibinder affinity screening